ANÁLISE DE CAPTURAS HÍBRIDAS PARA HPV EM MULHERES COM LESÃO INTRAEPITELIAL CERVICAL

Authors

DOI:

https://doi.org/10.53843/bms.v9i13.558

Keywords:

Uterine Cervical Neoplasms, Intraepithelial Lesion, High Grade Squamous Intraepithelial Lesions, Low Grade Squamous Intraepithelial Lesion, Preventive Medicine

Abstract

Introduction: It is known that the presence of HPV is closely related to the development of cervical intraepithelial lesions. In order to identify the viral presence in the organism, the search for DNA-HPV is used through the hybrid capture test. The present study aims to evaluate the findings of hybrid captures and compare them with the results of the anatomopathological examination of women with cervical intraepithelial lesions at a diagnostic pathology medical center. Methods: the search for secondary data was carried out through the analysis of reports of positive hybrid capture for HPV, as well as the anatomopathological examination suggestive of cervical intraepithelial lesion. The variables used were the patient's age, hybrid capture report and anatomopathological examination report. Results: The mean age of the studied patients was 30.14 years, and women with high-grade lesions had a higher mean age. As for the anatomopathological examination, most women had low-grade lesions. High-risk HPV was more prevalent both in women with low-grade and high-grade lesions. The sensitivity of the hybrid capture was 62.2%, specificity 28.9% and negative predictive value 63.2%. Discussion: The results obtained were lower than those in the literature, but they corroborate the current guidelines. Conclusion: The study suggests that hybrid capture be used as an auxiliary method for the diagnosis and follow-up of women with cervical injuries.

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Author Biographies

Mirelly Meister Arnold Rufino, Universidade do Extremo Sul Catarinense

Acadêmica de medicina

Thaís Marson Meneguzzo, Universidade do Extremo Sul Catarinense

Acadêmica de Medicina

Luana Amboni Canela, Universidade do Extremo Sul Catarinense

Acadêmica de medicina

Elizandra Ross Martins, Universidade do Extremo Sul Catarinense

Professora e pesquisadora do Curso de Medicina. Médica especialista em patologia.

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Published

18.01.2025

How to Cite

1.
Meister Arnold Rufino M, Marson Meneguzzo T, Amboni Canela L, Ross Martins E. ANÁLISE DE CAPTURAS HÍBRIDAS PARA HPV EM MULHERES COM LESÃO INTRAEPITELIAL CERVICAL. BMS [Internet]. 2025 Jan. 18 [cited 2025 Feb. 6];9(13). Available from: https://bms.ifmsabrazil.org/index.php/bms/article/view/558