RESTRIÇÃO DE CRESCIMENTO INTRAUTERINO (RCIU) COMO PARTE DA SÍNDROME ALCOÓLICA FETAL
DOI:
https://doi.org/10.53843/bms.v8i12.618Palavras-chave:
intrauterine growth restriction, pregnancy, alcoholism, toxic substances, fetal periodResumo
Introduction: An investigation was conducted on the effects of alcohol on pregnant women as a possible cause of intrauterine growth restriction. The American Pregnancy Association defines intrauterine growth restriction (IUGR) as a fetal weight below the 10th percentile for gestational age as determined by ultrasound.
Method: A search of medical literature was performed from January 2010 to January 2022. For this purpose, different scientific databases were used, which were: PUBMED, EBSCO and Google Scholar.
Results: The fetal period is the time of development from the ninth week to the moment of birth. The most severe form associated with alcohol consumption during pregnancy is Fetal Alcohol Syndrome, which requires a minimum consumption of 12 g per day of absolute alcohol for this syndrome to manifest itself. Infants whose mothers are chronic alcoholics show a characteristic pattern of defects including prenatal and postnatal growth deficiencies, mental deficiency, and other problems.
Discussion: Environmental factors influence fetal growth, and this has been increasingly emphasized with increasing evidence. With regard to the database collected from different research sources, we can confirm the great relationship that exists on the effects of alcohol consumption by pregnant women on fetal growth. Kazutoshi-cho's study on prenatal exposure to alcohol in Japanese women shows us that the consumption of a weekly dose of alcohol during the second and third trimester has a significant negative relationship with the decrease in body weight, body length and head circumference at birth.
Conclusion: Excessive alcohol consumption is highly associated with fetal growth restriction (fetal alcohol syndrome). The level of effects may be different depending on the frequency of exposure and dose.
Métricas
Referências
Sepulveda, E., Crispi, F., Pons, A., & Gratacos, E. (Noviembre de 2014). Restricción de crecimiento intrauterino. Revista Medica Clinica Las Condes, 6. doi: 10.1016/S0716-8640(14)70644-3 DOI: https://doi.org/10.1016/S0716-8640(14)70644-3
Silvia Maya-Enero, Sofia Martina Ramis-Fernández, Marta Astals-Vizcaino, Óscar García-Algar. Perfil neurocognitivo y conductual del trastorno del espectro alcohólico fetal. Anales de Pediatría, Volumen 95, Número 3, Septiembre 2021. Páginas 208.el-208.e9 DOI: https://doi.org/10.1016/j.anpedi.2020.12.015
Suarez, Hector Andres, & RIVOLTA, S. E. (2016). Trastornos del espectro alcohólico fetal. Biomarcadores del consumo de etanol durante la gestación. Revista De Salud Pública, 20(1), 52–58. https://doi.org/10.31052/1853.1180.v20.n1.12057 DOI: https://doi.org/10.31052/1853.1180.v20.n1.12057
Montoya Salas, Kattia. (2011). Síndrome alcohólico fetal. Medicina Legal de Costa Rica, 28 (2), 51-55. Recuperado el 09 de noviembre de 2022, de http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S140900152011000200006&Ing=en&tlng=es
Albu, A. R., Anca, A. F., Horhoianu, V. V., & Horhoianu, I. A. (2014). Predictive factors for intrauterine growth restriction. Journal of medicine and life, 7(2), 165–171.
Pimiento Infante, L. M. & Beltrán Avendaño, M. A. (2015). Restricción del crecimiento intrauterino: una aproximación al diagnóstico, seguimiento y manejo. Revista chilena de obstetricia y ginecología, 80(6), 493-502. https://doi.org/10.4067/s0717-75262015000600010 DOI: https://doi.org/10.4067/S0717-75262015000600010
Valenti E, Avila N, Amenabar S,Zanuttini E & Crespo H. (2017). RCIU (Restricción del Crecimiento Intrauterino). Federación Argentina de Sociedades de Ginecología y Obstetricia, Obtenido de: http:www.fasgo.org.ar/archivos/concensos/Actualización_consenso_RCIU_FASGO_2017.pdf
Moore KL, Persaud TVN, Torchia MG. Embriología Clínica. 11ª ed. Barcelona, España: Ed. Elsevier Saunders. 2020.
Carlson, M. B. (2014). Human Embryology and Developmental Biology, (5th Edition). Ed. Elsevier. DOI: https://doi.org/10.1016/B978-1-4557-2794-0.00010-3
AROS A, S. (2008h). Exposición fetal a alcohol. Revista chilena de pediatría, 79. https://doi.org/10.4067/s0370-41062008000700008 DOI: https://doi.org/10.4067/S0370-41062008000700008
Popova S, Lange S, Probst C, Gmel G, Rehm J. Estimation of national, regional, and global prevalence of alcohol use during pregnancy and fetal alcohol syndrome: a systematic review and meta-analysis. Lacet Glob Health [Internet] 2017 [acceso 3 de enero de 2021]; 5(3): 290-299. Disponible en: https://www.thelancet.com/journals/langlo/article/PIIS2214- 109X(17)30021-9/fulltext DOI: https://doi.org/10.1016/S2214-109X(17)30021-9
Chiodo LM, Cosmian C, Pereira K, Kent N, Sokoi RJ, Hannigan JH. Prenatal Alcohol Screening During Pregnancy by Midwives and Nurses. Alcohol Clin Exp Res. [Internet] 2019 [acceso 4 de enero de 2021]; 43(8): 1747-1758. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772020/ DOI: https://doi.org/10.1111/acer.14114
Popova, S., Lange, S., Shield, K., Burd, L. & Rehm, J. (2019). Prevalence of fetal alcohol spectrum disorder among special subpopulations: a systematic review and meta‐analysis. Addiction, 114(7), 1150-1172. https://doi.org/10.1111/add.14598 DOI: https://doi.org/10.1111/add.14598
Nowak, A., & Michno, A. (2019). FASD – Fetal Alcohol Syndrome Disorder. World Scientific News, (129), 242–254.
Charro Baena B, Rivas Olivera A, Raul Xavier M. Embarazo y alcohol: conocimientos, actitudes y opiniones de los profesionales sanitarios. Health and Addictions [Internet] 2019 [acceso 5 de enero de 2021]; 19(2):78-90. Disponible en: https://ojs.haaj.org/index.php?journal=haaj&page=article&op=vie w&path%5B%5D=445 DOI: https://doi.org/10.21134/haaj.v19i2.445
Blasco Alonso M, González Mesa E, Gálvez Montes M, Lozano Bravo I, Merino Galdón F, Cuenca Campos F et al. Exposición al tabaco, alcohol y drogas de abuso en gestantes. Estudio de prevalencia en gestantes de Málaga (España). Adicciones [Internet] 2015 [acceso 28 de diciembre de 2020]; 27(2). Disponible en: https://www.adicciones.es/index.php/adicciones/article/view/695/ 681 DOI: https://doi.org/10.20882/adicciones.695
Denny, L., Coles, S., & Blitz, R. (2017). Fetal Alcohol Syndrome and Fetal Alcohol Spectrum Disorders. American Family Physician, 96(8), 515–522.
Blanck-Lubarsch, M., Dirksen, D., Feldmann, R., Sauerland, C. & Hohoff, A. (2019). Tooth Malformations, DMFT Index, Speech Impairment and Oral Habits in Patients with Fetal Alcohol Syndrome. International Journal of Environmental Research and Public Health, 16(22), 4401. https://doi.org/10.3390/ijerph16224401 DOI: https://doi.org/10.3390/ijerph16224401
Wozniak, J. R., Riley, E. P. & Charness, M. E. (2019). Clinical presentation, diagnosis, and management of fetal alcohol spectrum disorder. The Lancet Neurology, 18(8), 760-770. https://doi.org/10.1016/s1474-4422(19)30150-4 DOI: https://doi.org/10.1016/S1474-4422(19)30150-4
Safety, N. A. F. (s. f). Metas mundiales de nutrición 2025: documento normativo sobre bajo peso al nacer. https://www.who.int/es/publications/i/item/WHO-NMH-NHD-14.5
Armengaud, J., Yzydorczyk, C., Siddeek, B., Peyter, A. & Simeoni, U. (2021). Intrauterine growth restriction: Clinical consequences on health and disease at adulthood. Reproductive Toxicology, 99, 168-176. https://doi.org/10.1016/j.reprotox.2020.10.005 DOI: https://doi.org/10.1016/j.reprotox.2020.10.005
Bendix, I., Miller, S. L. & Winterhager, E. (2020). Editorial: Causes and Consequences of Intrauterine Growth Restriction. Frontiers in Endocrinology, 11. https://doi.org/10.3389/fendo.2020.00205 DOI: https://doi.org/10.3389/fendo.2020.00205
Xiao, D., Kou, H., Gui, S., Ji, Z., Guo, Y., Wu, Y. & Wang, H. (2019). Age-Characteristic Changes of Glucose Metabolism, Pancreatic Morphology and Function in Male Offspring Rats Induced by Prenatal Ethanol Exposure. Frontiers in Endocrinology, 10. https://doi.org/10.3389/fendo.2019.00034 DOI: https://doi.org/10.3389/fendo.2019.00034
Cho K, Kobayashi S, Araki A, Miyashita C, Itoh S, Saijo Y, Ito Y, Sengoku K, Baba T, Minakami H, Nakamura Y, Kishi R; Japan Environment and Children’s Study Group. Prenatal alcohol exposure and adverse fetal growth restriction: findings from the Japan Environment and Children's Study. Pediatr Res. 2022 Jul;92(1):291-298. doi: 10.1038/s41390-021-01595-3. Epub 2021 Jun 4. PMID: 34088984. DOI: https://doi.org/10.1038/s41390-021-01595-3
Patra J, Bakker R, Irving H, Jaddoe VW, Malini S, Rehm J. Dose-response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)-a systematic review and meta-analyses. BJOG. 2011 Nov;118(12):1411-21. doi: 10.1111/j.1471-0528.2011.03050.x. Epub 2011 Jul 6. PMID: 21729235; PMCID: PMC3394156. DOI: https://doi.org/10.1111/j.1471-0528.2011.03050.x
Ishitsuka K, Hanada-Yamamoto K, Mezawa H, Saito-Abe M, Konishi M, Ohya Y; Japan Environment and Children’s Study Group. Determinants of Alcohol Consumption in Women Before and After Awareness of Conception. Matern Child Health J. 2020 Feb;24(2):165-176. doi: 10.1007/s10995-019-02840-2. PMID: 31853680. DOI: https://doi.org/10.1007/s10995-019-02840-2
Downloads
Publicado
Como Citar
Edição
Seção
Licença
Copyright (c) 2023 Jose Antonio Olguin Calvillo, Julieta Belen Delgadillo Aldana, Brenda Abigail Arteaga Vazquez, José Eugenio Guerra Cárdenas
Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
As licenças de usuário definem como os leitores e o público em geral podem usar o artigo sem precisar de outras permissões. As licenças públicas do Creative Commons fornecem um conjunto padrão de termos e condições que os criadores e outros detentores de direitos podem usar para compartilhar obras originais de autoria e outros materiais sujeitos a copyright e alguns outros direitos especificados na licença pública disponível em https://creativecommons.org/licenses/by/4.0/deed.pt_BR. Ao usar a 4.0 International Public License, a Brazilian Medical Students (BMS) concede ao público permissão para usar o material publicado sob os termos e condições especificados acordados pela revista. Ao exercer os direitos licenciados, os autores aceitam e concordam em obedecer aos termos e condições da Licença Pública Internacional Creative Commons Atribuição 4.0.
