Fat grafting in the treatment of complex wounds in the SUS: a case series
DOI:
https://doi.org/10.53843/eqnkyp19Keywords:
Allografts, Adipose Tissue, WoundsAbstract
Introduction: There is no gold standard therapy for the treatment of complex wounds, which promotes better aesthetic-functional results, in addition to reducing current morbidity and mortality rates and healthcare costs in Brazil. Fat grafting represents a promising therapeutic option due to its regenerative properties. Methods: This is a retrospective case series study, with analysis of electronic medical records of 4 patients who underwent fat grafting on complex wounds in a Reconstructive Plastic Surgery service, from October 2019 to October 2023. Results: All 4 patients had some serious decompensated comorbidity. Patient 1, with a 10 cm ulcer with bone and tendon exposure on the left ankle. Two fat grafts were performed with a vacuum dressing, followed by a dermal-epidermal graft on the lesion. Patient 2, with venous ulcers on the right leg. After fat grafting on the wounds, the patient did not want to remain hospitalized. The dressing was opened in an outpatient setting, and the bed was found to be rich in granulation tissue. Outpatient follow-up and simple dressings were carried out at the UBS. Patient 3, with infected varicose ulcers on the lower limbs with tendon exposure. Despite fat grafting, the wound developed extensive fibrin and a foul odor. We then opted for outpatient follow-up with local dressings. Patient 4, with a wound on the plantar surface of the right foot with tendon exposure. Seven days after debridement and angioplasty, fat grafting was performed on the lesion. However, the patient developed an indication for amputation through Vascular Surgery. Discussion: The application of fat grafting ensured the formation of granulation tissue in the wound bed and the success of other wound coverage techniques. The varied results prove that the success of the treatment depends on numerous factors directly related to the patients. Conclusion: Easy application, availability and low cost make fat grafting viable in the SUS Plastic Surgery Service.
References
1. Coltro PS, Ferreira MC, Batista BP, Nakamoto HA, Milcheski DA, Tuma Júnior P. Tratamento cirúrgico das feridas complexas: experiência da cirurgia plástica no Hospital das Clínicas da FMUSP. Revista De Medicina, 89(3-4), 153-157. https://doi.org/10.11606/issn.1679-9836.v89i3/4p153-157. DOI: https://doi.org/10.11606/issn.1679-9836.v89i3/4p153-157
2. Ferreira MC, Tuma P Jr, Carvalho VF, Kamamoto F. Complex wounds. Clinics (São Paulo). 2006 Dec;61(6):571-8. doi: 10.1590/s1807-59322006000600014. PMID: 17187095. DOI: https://doi.org/10.1590/S1807-59322006000600014
3. Pellon MA, Induced Auto-Regeneration with Adipose Tissue in Humans – Beyond Frontiers of Healing. JOJ Dermatol & Cosmet. 2020; 3(4): 555617. DOI: 10.19080/JOJDC.2020.03.555617. DOI: https://doi.org/10.19080/JOJDC.2020.03.555617
4. Luck J, Smith OJ, Malik D, Mosahebi A. Protocol for a systematic review of autologous fat grafting for wound healing. Syst Rev. 2018 Jul 18;7(1):99. doi: 10.1186/s13643-018-0769-7. PMID: 30021622; PMCID: PMC6052690. DOI: https://doi.org/10.1186/s13643-018-0769-7
5. Condé-Green A, Marano AA, Lee ES, Reisler T, Price LA, Milner SM, Granick MS. Fat Grafting and Adipose-Derived Regenerative Cells in Burn Wound Healing and Scarring: A Systematic Review of the Literature. Plast Reconstr Surg. 2016 Jan;137(1):302-312. doi: 10.1097/PRS.0000000000001918. PMID: 26710034. DOI: https://doi.org/10.1097/PRS.0000000000001918
6. Strong AL, Cederna PS, Rubin JP, Coleman SR, Levi B. The Current State of Fat Grafting: A Review of Harvesting, Processing, and Injection Techniques. Plast Reconstr Surg. 2015 Oct;136(4):897-912. doi: 10.1097/PRS.0000000000001590. PMID: 26086386; PMCID: PMC4833505. DOI: https://doi.org/10.1097/PRS.0000000000001590
7. Stasch T, Hoehne J, Huynh T, De Baerdemaeker R, Grandel S, Herold C. Débridement and Autologous Lipotransfer for Chronic Ulceration of the Diabetic Foot and Lower Limb Improves Wound Healing. Plast Reconstr Surg. 2015 Dec;136(6):1357-1366. doi: 10.1097/PRS.0000000000001819. PMID: 26273734. DOI: https://doi.org/10.1097/PRS.0000000000001819
8. Camargo, Paula Angeleli Bueno de et al. Uso de curativo a vácuo como terapia adjuvante na cicatrização de sítio cirúrgico infectado. Jornal Vascular Brasileiro [online]. 2016, v. 15, n. 4 [Acessado 3 Dezembro 2023], pp. 312-316. Disponível em: <https://doi.org/10.1590/1677-5449.002816>. Epub 05 Jan 2017. ISSN 1677-7301. https://doi.org/10.1590/1677-5449.002816. DOI: https://doi.org/10.1590/1677-5449.002816
9. SES DF. Técnica conhecida como curativo a vácuo acelera recuperação de feridas e queimaduras complexas, 2015. Disponível em: <https://www.saude.df.gov.br/web/guest/w/tecnica-conhecida-como-curativo-a-vacuo-acelera-recuperacao-de-feridas-e-queimaduras-complexas#:~:text=O%20custo%20do%20tratamento%20pode>. Acesso em: 16 out. 2023.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Anna Heloisa Tavares, Dayane Raquel de Paula, Giovana Knapik Batista, Bianca Biranoski, Maitê Matheus

This work is licensed under a Creative Commons Attribution 4.0 International License.
User licenses define how readers and the general public can use the article without needing other permissions. The Creative Commons public licenses provide a standard set of terms and conditions that creators and other rights holders can use to share original works of authorship and other material subjects to copyright and certain other rights specified in the public license available at https:// creativecommons.org/licenses/by/4.0/deed.pt_BR. Using the 4.0 International Public License, Brazilian Medical Students (BMS) grants the public permission to use published material under specified terms and conditions agreed to by the journal. By exercising the licensed rights, authors accept and agree to abide by the terms and conditions of the Creative Commons Attribution 4.0 International Public License.