PERFIL CLÍNICO E EPIDEMIOLÓGICO DE PACIENTES COM COLEDOCOLITÍASE SUBMETIDOS A COLANGIOPANCREATOGRAFIA RETRÓGRADA ENDOSCÓPICA
DOI:
https://doi.org/10.53843/bms.v10i14.924Keywords:
Cálculos biliares, Colangiopancreatografia Retrógrada Endoscópica, Ducto colédoco, Coledocolitíase, Colédoco, EpidemiologiaAbstract
INTRODUCTION: Choledocholithiasis is a condition characterized by the presence of stones in the common bile duct. The objective of this study was to analyze the clinical and epidemiological profile of patients diagnosed with this pathology, treated at a high-complexity hospital in southern Santa Catarina between 2018 and 2022. METHODS: Medical records of 121 patients with choledocholithiasis who underwent endoscopic retrograde cholangiopancreatography (ERCP) were evaluated. The data analyzed included age, sex, race, body mass index, comorbidities, clinical manifestations, diagnosis, type of treatment, and presence of periampullary diverticulum. RESULTS AND DISCUSSION: It was observed that 62% of the patients were female, and the average age was 56.5 years. It was noted that 38.8% of the individuals were overweight and 27.3% were obese. Furthermore, the clinical manifestations presented by 58.7% of the individuals were abdominal pain associated with jaundice, and the most commonly used diagnostic method was magnetic resonance cholangiography (76.0%). Additionally, the treatment most frequently used was ERCP, which was performed alone in 55.4% of the patients and in combination with laparoscopic surgery in 39.7% of the cases. Finally, periampullary diverticulum was found in 9.9% of the patients. CONCLUSION: This study highlighted the occurrence of choledocholithiasis in overweight and obese women; it also aligned with the literature regarding the presence of periampullary diverticula in patients with choledocholithiasis.
References
Arnaldo José Montiel-Roa, Sergio David Mora-Garbini, Antonella Dragotto-Galván, Brenda Margarita Rojas-Franco. Incidence of choledocholithiasis detected by intraoperative cholangiography in a high complexity hospital during period 2014-2018. Cirugía paraguaya. 2020 Aug 30;44(2):13–5. Disponível em: https://doi.org/10.18004/sopaci.2020.agosto.13 DOI: https://doi.org/10.18004/sopaci.2020.agosto.13
Alvarez chica L fernando, Rico-Juri JM, Carrero-Rivera SA, Castro-Villegas F. Coledocolitiasis y exploración laparoscópica de la vía biliar. Un estudio de cohorte. Revista Colombiana de Cirugía. 2021 Mar 9;36(2):301–11. Disponível em: https://doi.org/10.30944/20117582.558 DOI: https://doi.org/10.30944/20117582.558
Agostini  de FP, Hochhegger B, Forte GC, Susin LA, Difini JPM. ACCURACY OF ABBREVIATED PROTOCOL OF MAGNETIC RESONANCE CHOLANGIO-PANCREATOGRAPHY IN THE DIAGNOSIS OF CHOLEDOCHOLITHIASIS. Arquivos De Gastroenterologia [Internet]. 2022;59(2):188–92. Disponível em: https://pubmed.ncbi.nlm.nih.gov/35830027/ DOI: https://doi.org/10.1590/s0004-2803.202202000-35
BUXBAUM, J. L. et al. ASGE guideline on the role of endoscopy in the evaluation and management of choledocholithiasis. Gastrointestinal Endoscopy, v. 89, n. 6, p. 1075-1105.e15, jun. 2019. Disponível em: http://dx.doi.org/10.1016/j.gie.2018.10.001 DOI: https://doi.org/10.1016/j.gie.2018.10.001
Manes G, Paspatis G, Aabakken L, Anderloni A, Arvanitakis M, Ah-Soune P, et al. Endoscopic management of common bile duct stones: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2019 Apr 3;51(05):472–91. DOI: https://doi.org/10.1055/a-0862-0346
Cianci P, Restini E. Management of cholelithiasis with choledocholithiasis: Endoscopic and surgical approaches. World Journal of Gastroenterology. 2021 Jul 28;27(28):4536–54. Disponível em: http://dx.doi.org/10.3748/wjg.v27.i28.4536 DOI: https://doi.org/10.3748/wjg.v27.i28.4536
Wu Y, Xu CJ, Xu SF. Advances in Risk Factors for Recurrence of Common Bile Duct Stones. International Journal of Medical Sciences. 2021;18(4):1067–74. Disponível em: https://doi.org/10.7150/ijms.52974 DOI: https://doi.org/10.7150/ijms.52974
Zhang J, Ling X. Risk factors and management of primary choledocholithiasis: a systematic review. ANZ Journal of Surgery. 2020 Aug 19;91(4):530–6. Disponível em: http://dx.doi.org/10.1111/ans.16211 DOI: https://doi.org/10.1111/ans.16211
NASCIMENTO JHF do, TOMAZ SC, SOUZA-FILHO BM de, VIEIRA ATS, ANDRADE AB de, GUSMÃO-CUNHA A. A POPULATION STUDY ON GENDER AND ETHNICITY DIFFERENCES IN GALLBLADDER DISEASE IN BRAZIL. ABCD Arquivos Brasileiros de Cirurgia Digestiva (São Paulo). 2022;35. Disponível em: https://doi.org/10.1590/0102-672020210002e1652 DOI: https://doi.org/10.1590/0102-672020210002e1652
AGUIAR RGP de, SOUZA JÚNIOR FEA de, ROCHA JÚNIOR JLG, PESSOA FSR de P, SILVA LP da, CARMO GC do. CLINICAL AND EPIDEMIOLOGICAL EVALUATION OF COMPLICATIONS ASSOCIATED WITH GALLSTONES IN A TERTIARY HOSPITAL. Arquivos de Gastroenterologia. 2022 Sep;59(3):352–7. Disponível em: doi.org/10.1590/S0004-2803.202203000-64 DOI: https://doi.org/10.1590/s0004-2803.202203000-64
Chen J, Zhou H, Jin H, Liu K. The causal effects of thyroid function and lipids on cholelithiasis: A Mendelian randomization analysis. Frontiers in Endocrinology [Internet]. 2023 [cited 2023 Oct 29];14:1166740. Disponível em: https://doi.org/10.3389/fendo.2023.1166740 DOI: https://doi.org/10.3389/fendo.2023.1166740
Mei Y, Chen L, Peng CJ, Wang J, Zeng PF, Wang GX, et al. Diagnostic value of elevated serum carbohydrate antigen 199 level in acute cholangitis secondary to choledocholithiasis. World Journal of Clinical Cases [Internet]. 2018 Oct 6;6(11):441–6. Disponível em: https://pubmed.ncbi.nlm.nih.gov/30294608/ DOI: https://doi.org/10.12998/wjcc.v6.i11.441
Xu X, Qian J, Dai J, Sun Z. Endoscopic treatment for choledocholithiasis in asymptomatic patients. Journal of Gastroenterology and Hepatology. 2019 Aug 7;35(1):165–9. Disponível em: https://doi.org/10.1111/jgh.14790
Zouki J, Sidhom D, Bindon R, Sidhu T, Chan E, Lyon M. Choledocholithiasis: A Review of Management and Outcomes in a Regional Setting. Cureus [Internet]. 2023 Dec 1;15(12):e50223. Disponível em: https://pubmed.ncbi.nlm.nih.gov/38192960/ DOI: https://doi.org/10.7759/cureus.50223
Goyal H, Sachdeva S, Syed, Gupta S, Abhilash Perisetti, Ali A, et al. Early prediction of post-ERCP pancreatitis by post-procedure amylase and lipase levels: A systematic review and meta-analysis. 2022 Jul 1;10(07):E952–70. Disponível em: https://doi.org/10.1055/a-1793-9508 DOI: https://doi.org/10.1055/a-1793-9508
Mederos MA, Reber HA, Girgis MD. Acute Pancreatitis. JAMA. 2021 Jan 26;325(4):382–90. Disponível em: https://doi.org/10.1001/jama.2020.20317 DOI: https://doi.org/10.1001/jama.2020.20317
Manivasagam SS, Chandra J N, Shah S, Kuraria V, Manocha P. Single-Stage Laparoscopic Common Bile Duct Exploration and Cholecystectomy Versus Two-Stage Endoscopic Stone Extraction Followed by Laparoscopic Cholecystectomy for Patients With Cholelithiasis and Choledocholithiasis: A Systematic Review. Cureus [Internet]. 2024 Feb 1;16(2):e54685. Disponível em: https://pubmed.ncbi.nlm.nih.gov/38524041/ DOI: https://doi.org/10.7759/cureus.54685
Ruiz Pardo J, García Marín A, Ruescas García FJ, Jurado Román M, Scortechini M, Sagredo Rupérez MP, Valiente Carrillo J. Differences between residual and primary choledocholithiasis in cholecystectomy patients. Rev Esp Enferm Dig. 2020 Aug;112(8):615-619. Disponível em: https://doi.org/10.17235/reed.2020.6760/2019 DOI: https://doi.org/10.17235/reed.2020.6760/2019
Xu X, Qian J, Dai J, Sun Z. Endoscopic treatment for choledocholithiasis in asymptomatic patients. Journal of Gastroenterology and Hepatology. 2019 Aug 7;35(1):165–9. Disponível em: https://pubmed.ncbi.nlm.nih.gov/31334888/ DOI: https://doi.org/10.1111/jgh.14790
Karaahmet F, Kekilli M. The presence of periampullary diverticulum increased the complications of endoscopic retrograde cholangiopancreatography. European Journal of Gastroenterology & Hepatology. 2018 Sep;30(9):1009–12. Disponível em: https://doi.org/10.1097/meg.0000000000001172 DOI: https://doi.org/10.1097/MEG.0000000000001172
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Eduarda Deluca Muller, Fabielle Menezes Tolfo, Felipe Antônio Cacciatori, João de Bona Castelan Filho

This work is licensed under a Creative Commons Attribution 4.0 International License.
User licenses define how readers and the general public can use the article without needing other permissions. The Creative Commons public licenses provide a standard set of terms and conditions that creators and other rights holders can use to share original works of authorship and other material subjects to copyright and certain other rights specified in the public license available at https:// creativecommons.org/licenses/by/4.0/deed.pt_BR. Using the 4.0 International Public License, Brazilian Medical Students (BMS) grants the public permission to use published material under specified terms and conditions agreed to by the journal. By exercising the licensed rights, authors accept and agree to abide by the terms and conditions of the Creative Commons Attribution 4.0 International Public License.