The 10 years of biomedical research interest regarding the “exerkine” Irisin: a bibliometric review
The bibliometric review fo Irisin
DOI:
https://doi.org/10.53843/kntzay16Keywords:
Bibliometric analysis, FNDC5, Irisin, MyokinesAbstract
Irisin is a peptide secreted by skeletal muscle following physical exercise that is being widely studied since its discovery over the last decade. Although a robust number of studies have advanced on understanding of the effects of this myokine as an endocrine molecule and a potential candidate for therapeutic intervention for many disorders, there is no bibliometric data cataloguing the main advances regarding this myokine and generating guidelines for future directions. Objective: The aim of this study was to analyse the scientific production of biomedical journals on the myokine Irisin effects by a bibliometric analysis. Methods: A search was conducted in the Web of Science and Scopus databases using the keyword “Irisin'' to identify studies between 2001 and 2020. The data from all publications were exported and analysed on the Bibliometrix package using R software. Results: A total of 1579 papers were included, and the trend of annual publications showed a remarkable growth between 2012-2020. China and the Harvard Medical School (United States of America, USA) were the most productive countries and institutions in the Irisin research field, and the USA was the country with most cited manuscripts regarding Irisin. The current research hotspots of Irisin are in “metabolic diseases,” and “central nervous system-related diseases”. Conclusion: The authors summarize that Irisin is becoming frontier and focus on the health topics following the exercise adaptations in the upcoming years, which are worthy of further exploitation.
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