NARRATIVE REVIEW BASED ON CAUSES AND CONSEQUENCES OF THE ALICE IN WONDERLAND SYNDROME

Autores

DOI:

https://doi.org/10.53843/bms.v8i12.258

Palavras-chave:

Análise de Consequências, Análises de Causas Raiz, Síndrome de Alice no Pa´ís das Maravilhas

Resumo

INTRODUCTION: The Alice in Wonderland Syndrome (AIWS) is a rare clinical neurological condition, based on the presence of perception disorders which are interpreted by the patient as rare metamorphosing and depersonalization events. The main goal of this research is to analyze the causes and consequences of the Alice in Wonderland Syndrome. METHODOLOGY: In the process of creating this narrative review, the BVS, Scielo and PUBMED databases were consulted.  The following filters and inclusion criteria were used: English, Portuguese, Spanish AND last 5 years. RESULTS: The most common causes of AIWS are infections by the Epstein-Barr virus and migraines. Symptoms include visual illusions in which the patient sees altered object dimensions, changes in the shape (metamorphopsia) and even notice the disappearance of objects (palinopsia) and the appearance of animals (zoopsy). DISCUSSION: The analysis of the articles showed that the main cause of AIWS is infection by Epstein Barr virus. There were reports including other causes, such as: epilepsy, migraines, infections by other viruses, consequences of surgery and drugs and medications. The majority of patients include young people and children with female predominance. The physiopathology of this disease is not fully understood, but some studies believe that there's the involvement of the occipital, temporal, and parietal lobes. CONCLUSION: AIWS remains a poorly known and misdiagnosed syndrome. This instability in the diagnostic process is because no univocally accepted diagnostic criteria for this disease has been developed. Further studies must be performed to achieve better comprehension of the syndrome.

Métricas

Carregando Métricas ...

Referências

Shah, A.; Maganã, S. M.; E. Youssef, P. Do You See What I See? A Case of Alice in Wonderland Syndrome With EEG Correlate. Child Neurology Open, v. 7, p. 1-4, 1 jan. 2020. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294370/ DOI: https://doi.org/10.1177/2329048X20932714

O’Toole, Patrick ; Modestino, Edward Justin. Alice in Wonderland Syndrome: A real life version of Lewis Car-roll’s novel. Brain and Development, v. 39, n. 6. 2017 p. 470–474. https://pubmed.ncbi.nlm.nih.gov/28189272/ DOI: https://doi.org/10.1016/j.braindev.2017.01.004

Carroll L. Alice's adventures in Wonderland. New York: MacMillan; 1865.

Giulio Mastria; Mancini, Valentina; Alessandro Vigano; et al. Alice in Wonderland Syndrome: A Clinical and Pathophysiological Review. ResearchGate. 2016 https://www.hindawi.com/journals/bmri/2016/8243145/ DOI: https://doi.org/10.1155/2016/8243145

Rastogi, Reena Gogia; Vanderpluym, Juliana ; Lewis, Kara Stuart. Migrainous Aura, Visual Snow, and “Alice in Wonderland” Syndrome in Childhood. Seminars in Pe-diatric Neurology, v. 23, n. 1. 2016. p. 14–17. https://pubmed.ncbi.nlm.nih.gov/27017016/ DOI: https://doi.org/10.1016/j.spen.2016.01.006

Vara, F. J. M. et al. Síndrome de Alicia en el País de las Maravillas e infección por virus de Epstein-Barr. Pediatr. aten. prim, v. 21, n. 1139-7632, p. e67–e70, 2019. https://pesquisa.bvsalud.org/portal/resource/pt/ibc-184588

Kubota, Kazuo; Shikano, Hiroaki; Fujii, Hidehiko; et al. Alice in Wonderland syndrome associated with influen-za virus infection. Pediatrics International, v. 62, n. 12. 2020. p.1391–1393. https://pubmed.ncbi.nlm.nih.gov/33145932/ DOI: https://doi.org/10.1111/ped.14341

aniz-Mondolfi, Alberto E.; GIRALDO, José; Rodrigues-Morales, Alfonso J.; et al. Alice in Wonderland syndro-me: a novel neurological presentation of Zika virus in-fection. Journal of NeuroVirology, v. 24, n. 5. 2018. p. 660–663. https://pubmed.ncbi.nlm.nih.gov/30105501/ DOI: https://doi.org/10.1007/s13365-018-0645-1

Omata, T. et al. Alice in Wonderland syndrome associa-ted with mycoplasma infection. Pediatrics International, v. 58, n. 10, p. 1057–1059, 31 ago. 2016. https://pubmed.ncbi.nlm.nih.gov/27577175/ DOI: https://doi.org/10.1111/ped.13039

Trevizol, A. P. et al. Alice in Wonderland syndrome secondary to optical neuromyelitis caused by varicella. The Australian and New Zealand Journal of Psychiatry, v. 52, n. 8, p. 805–806, 1 ago. 2018. https://pubmed.ncbi.nlm.nih.gov/29716388/ DOI: https://doi.org/10.1177/0004867418772348

Kadia, B. M.; Ekabe, C. J.; Agborndip, E. Primary care challenges of an obscure case of “Alice in Wonderland” syndrome in a patient with severe malaria in a resource-constrained setting: a case report. BMC Infectious Di-seases, v. 17, n. 1, p. 1–4, 1 dez. 2017. https://pubmed.ncbi.nlm.nih.gov/29272995/ DOI: https://doi.org/10.1186/s12879-017-2918-3

Fonseca, R. S. S. et al. Síndrome de Alicia en el país de las maravillas secundario a consumo de montelukast. Presentación de caso. Revista Médica Electrónica, v. 43, n. 2, p. 3222–3230, 1 abr. 2021. https://www.google.com/url?q=https://pesquisa.bvsalud.org/portal/resource/pt/biblio-1251939&sa=D&source=editors&ust=1629675579876000&usg=AOvVaw2iOrkwuZlW1oYOLn1GZf1E

Entezami, P. et al. Transient Episode of Alice in Wonder-land Syndrome After Ventriculoatrial Shunt Revision. World Neurosurgery, v. 121, n. , p. 149–151, jan. 2019. https://pubmed.ncbi.nlm.nih.gov/30326315/ DOI: https://doi.org/10.1016/j.wneu.2018.10.041

Chirchiglia, D.; Chirchiglia, P.; Marotta, R. A singular association of migraine with brainstem aura and Alice in Wonderland syndrome. Child’s Nervous System, v. 35, n. 8, p. 1435–1437, 2 maio 2019. https://pubmed.ncbi.nlm.nih.gov/31049666/ DOI: https://doi.org/10.1007/s00381-019-04170-8

Mastria, G. et al. Temporal–occipital glioblastoma pre-senting with Alice in Wonderland Syndrome in a patient with a long-time history of migraine without aura. Neu-rocase, v. 24, n. 5-6, p. 242–244, 2 nov. 2018. https://pubmed.ncbi.nlm.nih.gov/30599804/ DOI: https://doi.org/10.1080/13554794.2018.1562079

Beh, Shin C.; Masrour, Shamin; Smith, Stacy V.; et al. Clinical characteristics of Alice in Wonderland syndrome in a cohort with vestibular migraine. Neurology: Clinical Practice, v. 8, n. 5. 2018. p. 389–396. https://pubmed.ncbi.nlm.nih.gov/30564492/#:~:text=We%20observed%20several%20rare%20and,AIWS%20and%20VM%20with%20migraine DOI: https://doi.org/10.1212/CPJ.0000000000000518

Matsuura, Kazuki; Ishikura, Ryoko; Oguri, Masayoshi; et al. Atypical Symptoms in Migraine-Related Alice in Wonderland Syndrome: Expansion of the Phenotype and Reflection on the Pathomechanism. Yonago Acta Medica, v. 62, n. 1. 2019. p. 163–165. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437396/ DOI: https://doi.org/10.33160/yam.2019.03.023

Palacio-Sanchez, Leonardo ; Sebastián, Juan. Breve historia del síndrome de Alicia en el país de las maravil-las: perspectiva. Repert. med. cir. , 2017. p. 256–257. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-909789 DOI: https://doi.org/10.1016/j.reper.2017.08.010

Camacho Velasquez, JL; Rivero Sanz, E; Tejero Juste, C; et al. Síndrome de Alicia en el país de las maravillas en patología cerebrovascular. Neurología (Barc., Ed. impr.), v. 31, n. 6. 2016. p. 418–420, 2016. https://pesquisa.bvsalud.org/portal/resource/pt/ibc-154458 DOI: https://doi.org/10.1016/j.nrl.2014.09.009

Farooq, Osman ; Fine, Edward J. Alice in Wonderland Syndrome: A Historical and Medical Review. Pediatric Neurology, v. 77.2017. p. 5–11. https://pubmed.ncbi.nlm.nih.gov/29074056/ DOI: https://doi.org/10.1016/j.pediatrneurol.2017.08.008

Mastria, Giulio; Mancini, Valentina; Cesare, Marco Di; et al. Prevalence and characteristics of Alice in Wonder-land Syndrome in adult migraineurs: Perspectives from a tertiary referral headache unit. Cephalalgia, v. 41, n. 5. 2020. p. 515–524. https://pubmed.ncbi.nlm.nih.gov/33167711/ DOI: https://doi.org/10.1177/0333102420968245

Gómez-Sanchez, Daniel; Ros-Cervera, Gonzalo; Pérez-Verdú, Julia; et al. Aura sin migraña o síndrome de Ali-cia en el País de las Maravillas: Caso clínico pediátrico. Arch. argent. pediatr. 2019. p. 34–36. https://pesquisa.bvsalud.org/portal/resource/pt/biblio-983776

García-Cabo, C. et al. Alice in Wonderland syndrome as the initial and sole manifestation of ischaemic stroke. Neurologia (Barcelona, Spain), v. 34, n. 7, p. 487–488, 1 set. 2019. https://pubmed.ncbi.nlm.nih.gov/28081974/ DOI: https://doi.org/10.1016/j.nrleng.2018.10.009

Blom, J. D.; Nanuashvili, N.; Waters, F. Time Distortions: A Systematic Review of Cases Characteristic of Alice in Wonderland Syndrome. Frontiers in Psychiatry, v. 12, 7 may 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8138562/ DOI: https://doi.org/10.3389/fpsyt.2021.668633

Yokoyama, T. et al. A case of recurrent depressive di-sorder presenting with Alice in Wonderland syndrome: psychopathology and pre- and post-treatment FDG-PET findings. BMC Psychiatry, v. 17, n. 1, 27 April 2017. https://pubmed.ncbi.nlm.nih.gov/28449649/ DOI: https://doi.org/10.1186/s12888-017-1314-2

Vara, F. J. M. et al. Síndrome de Alicia en el País de las Maravillas e infección por virus de Epstein-Barr. Pediatr. aten. prim, v. 21, n. 1139-7632, p. e67–e70, 2019. https://pesquisa.bvsalud.org/portal/resource/pt/ibc-184588

Rocha, A. P. et al. Síndrome de Alice no país das mara-vilhas e reativação de infecção por Epstein-Barr. Rev. bras. neurol, v. 55, p. 35–37, 2019. https://pesquisa.bvsalud.org/portal/resource/pt/ibc-184588

Downloads

Publicado

03.02.2024

Como Citar

1.
Mota E, Menezes ALA, Castro MEPC de. NARRATIVE REVIEW BASED ON CAUSES AND CONSEQUENCES OF THE ALICE IN WONDERLAND SYNDROME. BMS [Internet]. 3º de fevereiro de 2024 [citado 1º de maio de 2024];8(12):258. Disponível em: https://bms.ifmsabrazil.org/index.php/bms/article/view/258